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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCAM
All Species:
26.36
Human Site:
S614
Identified Species:
58
UniProt:
P43121
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43121
NP_006491.2
646
71607
S614
E
L
V
V
E
V
K
S
D
K
L
P
E
E
M
Chimpanzee
Pan troglodytes
XP_001149681
1230
134039
S1198
E
F
V
V
E
V
K
S
D
K
L
P
E
E
M
Rhesus Macaque
Macaca mulatta
XP_001096935
753
82173
S721
E
F
V
V
E
V
K
S
D
K
L
P
E
E
M
Dog
Lupus familis
XP_546486
813
88440
S781
E
F
V
V
E
V
K
S
D
K
L
P
E
E
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2Y2
648
71527
S616
E
F
V
V
E
V
K
S
D
K
L
P
E
E
M
Rat
Rattus norvegicus
Q9EPF2
648
71309
S616
E
F
V
V
E
V
K
S
D
K
L
P
E
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517756
394
43137
N363
G
T
P
N
L
T
K
N
I
N
D
L
K
L
L
Chicken
Gallus gallus
P42292
588
65708
V547
G
L
L
L
V
A
L
V
A
G
V
V
Y
W
L
Frog
Xenopus laevis
NP_001085893
605
65914
S574
S
L
A
Q
D
P
A
S
G
E
L
A
V
E
L
Zebra Danio
Brachydanio rerio
Q90460
564
61255
Y527
A
A
L
V
G
L
I
Y
W
L
Y
I
K
K
T
Tiger Blowfish
Takifugu rubipres
NP_001092127
575
62314
S541
Y
W
V
Y
M
K
K
S
K
Q
G
S
W
K
T
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.8
81.6
65.4
N.A.
76.2
75.3
N.A.
23.2
25.8
31.8
24.9
25.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
52.2
83.5
69.9
N.A.
87.5
87.3
N.A.
33.1
45.9
48.4
43.3
43
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
93.3
N.A.
93.3
93.3
N.A.
6.6
6.6
26.6
6.6
20
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
93.3
93.3
N.A.
26.6
33.3
46.6
33.3
33.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
0
0
10
10
0
10
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
55
0
10
0
0
0
0
% D
% Glu:
55
0
0
0
55
0
0
0
0
10
0
0
55
64
0
% E
% Phe:
0
46
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
0
0
0
10
0
0
0
10
10
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
10
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
10
73
0
10
55
0
0
19
19
0
% K
% Leu:
0
28
19
10
10
10
10
0
0
10
64
10
0
10
28
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
55
% M
% Asn:
0
0
0
10
0
0
0
10
0
10
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
10
0
0
0
0
0
55
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
73
0
0
0
10
0
0
0
% S
% Thr:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
19
% T
% Val:
0
0
64
64
10
55
0
10
0
0
10
10
10
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
10
0
0
0
10
10
0
% W
% Tyr:
10
0
0
10
0
0
0
10
0
0
10
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _